Suppose you want to choose between two different vanes on your outdoor arrow set.

Go to Setup → Quiver and create a new arrowset. In this example it is named "2015 vanes test". Make it your default set to shoot with the coming days.
Fill it up with the number of arrows you have to test. In this example, 12 arrows are used. Put one type of vanes on halve of the set, and the other type of vanes on the other halve. Use two different colored nocks in each set. In this example the arrows with vane type A have orange nocks and the arrows with vanes type B have blue nocks
Create a match and shoot it with your test arrowset. In this example a match of 12 ends of 8 arrows is going to be shot. Important: Choose a nock color (let's say the orange ones) and set your sight correct for this type of arrow before starting to plot. Do this each day and for each match that your plotting. Always pick the same color to set your sight, and once you start plotting, don't move your sight!
Make sure that in plotting your match, arrow identification (Options → Match Input → Confirm arrow) is turned on. Shoot arrows randomly choosing orange and blue and plot them.
Identifying arrows can be done on nock color only. No need to look at the exact arrow numbers, just plot the colors. For each orange nock, choose an orange arrow and for blue nocks pick any blue arrow.
When the match is finished. One more thing to do. Select the match and add a tag to it, so later it is easy to find when filtering arrows. Tag it by long pressing the Match → Tag
In this example the match is tagged with "Tuning vane A or B".
The more matches are shot, the more information is gathered and the more accurate the result. Make sure each match is tagged with the same tag and shot and plotted the same way. Shooting at different distances and different target faces is no problem! Artemis is going to take all of that into account.
Go to Analysis → Multiview. Select the first filter, turn it on and give it a name (in this example "Orange (vane A)"). Choose all shots with tag "Tuning vane A or B", and...
...choose the test arrowset (in this example "2015 vanes test") and pick the orange nocks.
Create a second filter for the blue nocks. Choose all shots with tag "Tuning vane A or B" and select the arrow set "2015 vanes test" and check the arrows with blue nocks. 
Finally, compare them on a 70m 122cm target face and pick your choice of vane. In this example, the second vane (vane B) had a bit more offset and thus creates a bit more drag, but its groups are way better than vane A.  So, pick the best (smallest) group. The groups don’t necessarily need to be in the center because the sight was set for one option only (and this may not be option with the tightest group)